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Neuro Library · World Stroke Day 2026

From stroke recognition to mechanical thrombectomy: why every minute matters

Tissue is brain. Time is brain. Every minute counts. A patient journey from the first warning sign to emergency imaging, reperfusion treatment and meaningful recovery.

Recognize

Use BEFAST: sudden Balance, Eye, Face, Arm or Speech change means it is Time to call emergency services.

Reperfuse

Eligible patients may receive intravenous thrombolysis, mechanical thrombectomy, or both—without avoidable delay.

Recover

Specialist Stroke Unit care and early physiotherapy, speech, swallowing, occupational and cognitive rehabilitation improve recovery.

01 · World Stroke Day

Every M1nute Counts

World Stroke Day is marked on 29 October. The 2026 World Stroke Organization campaign focuses on symptom awareness and the need to #ActFAST: stroke can happen without warning, and early emergency care can save life and brain function.

A stroke occurs when blood flow to part of the brain is blocked or when a vessel ruptures. Symptoms depend on the affected brain region and may be painless. Never wait to see whether they disappear.

02 · Recognition

BEFAST: spot the signs, save a brain

BEFAST extends the familiar FAST message to include posterior-circulation symptoms. Even one sudden sign is enough to trigger an emergency response.

  • B · Balance: sudden dizziness, loss of balance, coordination or ability to walk
  • E · Eyes: sudden loss, blurring or doubling of vision
  • F · Face: one side droops or feels numb
  • A · Arms: weakness or numbness of one arm or leg
  • S · Speech: slurred speech, wrong words, inability to speak or understand
  • T · Time: call emergency services immediately

03 · Hospital response

The Stroke Code shortens door-to-treatment time

The emergency team checks airway, oxygenation, circulation, blood glucose, medicines, time last known well and the neurological deficit. A coordinated Stroke Code alerts neurology, neuroradiology, emergency medicine, nursing, laboratory and the angiography team in parallel.

The goal is not simply to complete tests—it is to identify the type of stroke and the safest effective treatment as rapidly as possible.

04 · Advanced neuroimaging

CT, CTA and perfusion answer different questions

Non-contrast CT rapidly excludes intracranial haemorrhage and estimates early ischaemic change. CT angiography of the head and neck identifies a large-vessel occlusion, stenosis, dissection or aneurysmal source and maps the access route for treatment.

CT perfusion or MRI can estimate irreversibly injured core and potentially salvageable penumbra in selected patients, including wake-up or late-window stroke. Advanced imaging should support fast decisions and must not delay treatment that is already indicated.

World Stroke Day 2026 infographic showing BEFAST, stroke imaging, endovascular treatment and rehabilitation
01 · World Stroke Day 2026World Stroke Day 2026 · BEFAST recognition, Stroke Code, advanced imaging, endovascular therapy and rehabilitation.
World Stroke Day 2026 poster with an artistic brain and the message Every Minute Matters
02 · Every Minute MattersTissue is brain. Time is brain. Synthetic educational artwork in the tsinasneuro.gr palette.

05 · Reperfusion therapy

Intravenous thrombolysis and mechanical thrombectomy

Eligible patients with disabling acute ischaemic stroke may receive intravenous alteplase or tenecteplase, usually within 4.5 hours. Selected patients with unknown onset or 4.5–9 hours may also qualify using advanced imaging criteria.

Mechanical thrombectomy removes a clot from a large intracranial artery using aspiration, a stent retriever or both. It is standard treatment for suitable large-vessel occlusions and can benefit carefully selected patients up to 24 hours, including some patients with a larger ischaemic core or basilar artery occlusion. When both thrombolysis and thrombectomy are indicated, thrombectomy should not be delayed to wait for improvement.

06 · Modern selection

Time is brain—but tissue is brain

Every minute without reperfusion can cost viable brain, so speed always matters. Yet people lose tissue at different rates depending on collateral circulation, occlusion site and physiology.

The tissue-based model uses clinical findings and imaging to identify patients who still have salvageable brain despite a late presentation. It expands treatment opportunities; it does not make delay safe. The best outcome still comes from recognizing symptoms and reaching an appropriate stroke centre immediately.

07 · After reperfusion

Dedicated Stroke Unit care continues the treatment

Reopening an artery is the beginning of the next phase. Specialist monitoring detects haemorrhage, swelling, recurrent stroke, rhythm disturbance, blood-pressure problems, fever, glucose disturbance and swallowing difficulty.

Secondary prevention is tailored to the cause and may include antithrombotic treatment, management of atrial fibrillation, carotid disease, blood pressure, diabetes, cholesterol, smoking and lifestyle. Follow-up imaging is selected when it can change care.

08 · Recovery

Rehabilitation builds the path back to independence

Rehabilitation should begin as soon as the patient is medically stable. Physiotherapy supports movement, strength and balance; occupational therapy restores daily activities; speech and language therapy addresses communication and swallowing; cognitive and psychological care supports memory, attention, mood and adjustment.

Recovery is individual and can continue for months or years. Family education, realistic goals, prevention of complications and coordinated community follow-up are part of modern stroke care—not optional extras.

09 · Evidence

Clinical references

01
World Stroke Day 2026 · Every M1nute CountsWorld Stroke Organization
02
2026 Guideline for the Early Management of Acute Ischemic StrokeAmerican Heart Association / American Stroke Association
03
Stroke · Diagnosis, treatment and rehabilitationWorld Health Organization
04
Endovascular Treatment Beyond the 24-Hour MarkEuropean Stroke Organisation